White Powder Drugs Local Anesthetic Powder Bupivacaine HCL CAS 14252-80-3

Basic info

Bupivacaine hydrochloride
CAS: 14252-80-3
Purity: 99%
MW: 324.89
MF: C18H28N2O. ClH
Appearance: White powder
Package: 25kg/cardboard
Grade Standard:UPS/BP
Export Markets:Global
Origin:China
Production Capacity:5000 kg /Month
Product Categories: Ntermediates & Fine Chemicals; Pharmaceuticals; Sodium channel; Amines; Aromatics; Heterocycles
Usage: Sodium channel blocker, local anesthetic.

Description

Anesthesia, local- Proparacaine and tetracaine are indicated to produce local anesthesia of short duration for ophthalmic procedures including measurement of intraocular pressure, removal of foreign bodies and sutures, and conjunctival and corneal scraping in diagnosis and gonioscopy.

Applications

Proparacaine hydrochloride and tetracaine are also indicated to produce local anesthesia prior to surgical procedures such as cataract extraction and pterygium excision, usually as an adjunct to locally injected anesthetics.

Ophthalmic solutions used for intraocular procedures should be preservative-free. Preservatives may cause damage to the corneal epithelium if a significant quantity of solutionenters the eye through the incision.

Bupivacaine, marketed under the brand name Marcaine among others, is a medication used to decrease feeling in a specific area.It is used by injecting it into the area, around a nerve that supplies the area, or into the spinal canal's epidural space. It is available mixed with a small amount of epinephrineto make it last longer.It typically begins working within 15 minutes and lasts for 2 to 8 hours.

Possible side effects include sleepiness, muscle twitching, ringing in the ears, changes in vision, low blood pressure, and an irregular heart rate. Concerns exist that injecting it into a joint can cause problems with the cartilage. Concentrated bupivacaine is not recommended for epidural freezing. Epidural freezing may also increase the length of labor. It is a local anaesthetic of the amide group.

uses

Bupivacaine is indicated for local infiltration, peripheral nerve block, sympathetic nerve block, andepidural and caudal blocks. It is sometimes used in combination with epinephrine to prevent systemic absorption and extend the duration of action. The 0.75% (most concentrated) formulation is used inretrobulbar block.It is the most commonly used local anesthetic in epidural anesthesia during labor, as well as in postoperative pain management.

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